منابع مشابه
Genetics of essential hypertension.
Essential hypertension affects 1 billion people worldwide and its genetic basis is well established. For this review we surveyed the literature on the genetics of hypertension during the past 18 months and we now report the highlights. There has been publication of the two largest genome scans for blood pressure and new loci including significant linkage to chromosome 6q have been reported. The...
متن کاملGenetics of essential hypertension: from families to genes.
Family studies demonstrated the contribution of genetic factors to the development of primary hypertension. However, the transition from this phenomenologic-biometric approach to the molecular-genetic one is more difficult. This last approach is mainly based on the Mendel paradigm; that is, the dissection of the poligenic complexity of hypertension is brought about on the assumption that the in...
متن کاملGenetics of essential tremor.
Essential tremor (ET), the cause of which remains poorly understood, is one of the most common neurological disorders. While environmental agents have been proposed to play a role, genetic factors are believed to contribute to its onset. Thus far, three gene loci (ETM1 on 3q13, ETM2 on 2p24.1 and a locus on 6p23) have been identified in patients and families with the disorder. In addition, a Se...
متن کاملPoint of View Genetics of Essential Hypertension From the Unimodal - Bimodal Controversy to Molecular Technology
THE aim of this brief review is to provide researchers involved in investigating the pathogenesis of essential hypertension with a historical perspective of genetic studies on the subject and to list some of the problems that should be taken into account when considering the hypothesis that a given biochemical mechanism may be involved in causing essential or genetic types of hypertension. Beca...
متن کاملPoint of View Genetics of Essential Hypertension From the Unimodal - Bimodal Controversy
THE aim of this brief review is to provide researchers involved in investigating the pathogenesis of essential hypertension with a historical perspective of genetic studies on the subject and to list some of the problems that should be taken into account when considering the hypothesis that a given biochemical mechanism may be involved in causing essential or genetic types of hypertension. Beca...
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ژورنال
عنوان ژورنال: Human Heredity
سال: 1957
ISSN: 0001-5652,1423-0062
DOI: 10.1159/000150944